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Outside the brain, dopamine is synthesized in several tissues including the gastrointestinal system where its actions reduce gastrointestinal motility, the pancreas where its actions inhibit insulin synthesis, and in the kidneys where its actions increase sodium excretion and urinary output

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When consumed naturally through foods, these nutrients are unlikely to cause harm, even when consumed in large amounts

This could impact their mental health if not adequately addressed

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Soluble Klotho regulates bone differentiation by upregulating expression of the transcription factor EGR-1